But even if you have a low RDW, still you may have a blood disease. A CBC test measures blood components such as red blood cells, white blood cells, and platelets as well as determines the number and type of blood cells. Suppose your RDW blood test results indicate that you have anaemia. In that case, you need to undergo treatment to increase the capacity of your red blood cells.
Based on the severity of your existing condition, your doctor may recommend medications, iron supplements and ask you to make changes in your diet. If your RDW is normal and the MCV is also normal, then you may still have anaemia due to blood loss or a chronic medical condition.
When your RDW is normal, but the MCV is low, then it can be a sign of anaemia as a result of thalassemia or a chronic condition. If other blood components are affected, it may indicate aplastic anaemia inability of the body to produce sufficient blood cells. High RDW If your results are above the normal RDW range, it is called a high RDW count, which can be a sign of: Microcytic anaemia: It is a condition characterised by the presence of red blood cells that are smaller than its normal size.
Macrocytic anaemia: It is a condition characterised by the presence of red blood cells that are larger than its normal size. A person is likely to feel a slight scratching or stinging sensation when the needle breaks the skin.
The blood sample will flow from the needle into a tube. Once the tube is full, the medical professional will remove the needle. They will often instruct the person to hold a piece of gauze against the site to stop any bleeding, before applying a bandage. The blood sample is then sent to a lab, where a technician will check for red cell size and distribution. RDW results describe the variation in size and volume of red blood cells in a sample. Results may be normal or high, and the ranges are nuanced.
A result in the normal range for an adult female will be A person with a normal result may still have an underlying condition. An MCV test measures the average volume of a red blood cell. Results may show:. In , researchers concluded that a high RDW result might be linked to poor outcomes in people with heart failure , or further cardiovascular events in people who have experienced a heart attack. Anemia can be treated with medications, dietary changes, and supplements.
However, untreated anemia can lead to severe complications. Which factors can reduce the RDW? Which diseases can reduce your RDW? What can I do to increase the RDW level in the blood? Which values are considered a low RDW level in the blood? There is no disease with a RDW percentage below normal range. Frances Fischbach. Marshall B. This condition is called anisocytosis [ 2 , 3 ].
Causes listed below are commonly associated with high RDW. If your RDW is high, work with your doctor or another health care professional to get an accurate diagnosis. This happens because all of these nutrients are needed to produce healthy red blood cells.
Any of these deficiencies can eventually lead to anemia. Alcoholics can have a high RDW without having liver disease. This is because alcohol can have toxic effects on red blood cells [ 13 ]. RDW is increased in various liver diseases, including hepatitis, alcoholic liver cirrhosis, biliary cirrhosis, and liver cancer [ 14 , 15 , 16 ].
Inflammatory cytokines can hinder red blood cell production, and thereby increase RDW levels. In addition, oxidative stress that often accompanies chronic inflammation can decrease the lifespan of red blood cells and further increase RDW values [ 6 , 7 ].
If a person has many blood transfusions, their RDW can increase due to the differences in blood cells between the donor and the recipient [ 12 , 31 ]. Bleeding in Injuries increase RDW [ 32 ]. Bleeding may not necessarily be visible, as is the case with gut bleeding [ 33 , 34 ]. Erythropoietin , a hormone produced by the kidneys, is needed for the production and maturation of red blood cells. Abnormal production of this hormone happens in kidney disease leading to increased RDW [ 1 ].
People with decreased kidney function have higher RDW levels [ 35 ]. In a study of over RDW is also affected by shift work. RDW is higher in people with sleep apnea [ 38 , 39 ]. Hereditary red blood cell disorders, such as sickle cell anemia, thalassemia, and spherocytosis can increase RDW [ 12 , 40 , 12 ]. In all of these disorders red blood cells become misshapen.
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